Objectives and Overview 

  Eating habits in developing countries have become westernized, resulting the spread of tooth decay in deciduous and young permanent teeth in children. However, these children can not be treated because of economic disparities, and it interferes with the healthy growth of them resulting a big issue of our world. In addition, in developed countries where aging has progressed, the number of tooth decay on tooth root of old people is increasing, and this is a common issue that leads to a decrease of QOL and an increase of medical expenses. Until now, although the problem was addressed using a tooth decay inhibitor, the problem remains that the tooth is blackened. The purpose of this project is to develop a preparation with the action of dentin fortification and tooth decay sterilization that suppresses early tooth decay without discoloration of tooth, and to be able to apply at low cost worldwide. Collaborating with the Professor Yuta Nishina of our university, we are accumulating basic data indicating effectiveness by applying the adsorptive action of graphene oxide, which is a distinctive material that has been modified to be inexpensively producible. 

Future plan

 　It can be applied inexpensively in any part of the world with economic disparities, and culturally acceptable with the formulation for sustained and uncolored characters. It is preparing for to obtain the intellectual property.