Development of new bone inducing materials for a lifelong health society

Objectives

  Bone diseases and fractures are one of the leading causes associated with poor patient quality of life particularly in the ageing society. At the Department of Biomaterials, we are developing new technologies and materials to promote bone regeneration.

Approach

  Based on a unique approach to evaluate the detailed process of bone formation from the Material Science and Life Science viewpoints, we found that cell membrane nanofragments originated from chondrocyte burst were the nucleation site for bone formation. These results allowed the development of unprecedented rapid bone tissue synthesis in vitro.  Additionally, it may provide opportunities for collaboration with industries, government, and universities and the society overall, by  improving the access to high-quality basic healthcare services.

1- Identification of cell membrane nanofragments as nucleation site for mineral formation.
2- Fabrication of artificial cell nanofragments for in vitro mineralization.

 

URL

http://www.okayama-u.ac.jp/user/biomat/

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